Depogy tablets contain dapoxetine, a selective serotonin reuptake inhibitor (SSRI) that is specifically used to treat and prevent premature ejaculation (PE) in men.
What is Depogy used for?
Depogy 30mg (dapoxetine 30mg) are used to treat premature ejaculation (PE), which is one of the most common causes of sexual dysfunction in men. It is defined as early ejaculation with minimal sexual stimulation before or soon after penetration, and can cause distress and problems with relationships. Depogy is used to improve control over ejaculation and increase the time interval before ejaculation occurs during intercourse, for men with persistent or recurrent PE.
How does Depogy work?
Depogy tablets 30mg contain dapoxetine 30mg, a selective serotonin reuptake inhibitor (SSRI) that is used specifically for premature ejaculation (PE), as it has a rapid onset of action, with maximum effect within 1-2 hours and a short half-life, which means that it is rapidly eliminated from the body within 24 hours. Ejaculation is a reflex that is mediated by the sympathetic nervous system.
When sexual stimulation has reached a certain threshold, sensory nerve cells in the spinal cord are activated and nerve impulses are sent to the brain, which then send messages back to motor neurones controlling the muscles in the penis that contract to effect ejaculation. The ejaculation reflex is thought to be mediated by serotonin, a specific brain chemical or neurotransmitter that is involved is transmitting nerve signals, which enables brain cells to communicate. Low levels of serotonin in certain areas of the brain are thought to be responsible for causing PE.
Dapoxetine in Depogy blocks the reuptake of serotonin from the synapse, which is the gap between nerve cells across which chemical messages are sent from one nerve cell to another. If the re-uptake of serotonin by the first nerve cell (pre-synaptic) is blocked, this means that there is more serotonin remaining for the receiving nerve cell (post-synaptic), which allows nerve cells to communicate with each other for longer. This action of dapoxetine in Depogy 30 helps prolong the ability to maintain sexual activity without premature ejaculation and maintain control over ejaculation for longer.
What does Depogy contain?
Depogy tablets 30mg contain active ingredient dapoxetine, a selective serotonin reuptake inhibitor (SSRI) that is used to treat and prevent persistent or recurrent premature ejaculation (PE). They also contain : lactose, cellulose-microcrystalline, croscarmellose sodium, silica-colloidal anhydrous, magnesium stearate, hypromellose, titanium dioxide, iron oxide black, iron oxide yellow.
What are the side effects of Depogy?
The most commonly reported side effects when taking Depogy tablets30mg include, headache, gastrointestinal upset (nausea, diarrhoea, dry mouth, abdominal discomfort), dizziness, drowsiness, tremor, difficulty sleeping, increased blood pressure, erectile dysfunction, reduced libido.
What medications interact with Depogy?
Several medications interact with Depogy tablets 30mg and should either not be taken while you are taking Depogy or only after discussion and instruction from your doctor:
Drugs that cause a serious reaction with Depogy: monoamine oxidase inhibitors for depression, thioridazine for schizophrenia, the anticoagulant warfarin increases risk of bleeding, NSAIDs like aspirin or ibuprofen St. John´s Wort, migraine medicines like sumatriptan, the analgesic tramadol, SSRI antidepressants like paroxetine or citalopram, SNRI antidepressants like venlafaxine, lithium for mood disorders,
Drugs that affect Depogy: thioridazine for schizophrenia, antifungals like ketoconazole, antibiotics like erythromycin, HIV treatments like ritonavir and atazanavir, calcium channel blockers like diltiazem for hypertension
How should Depogy be taken?
You should take your Depogy tablets 30mg swallowed whole with a glass of water with or without food. You should take your Depogy tablet 1-3 hours before planned sexual activity.
How should Depogy be stored?
You should store your Depogy tablets below 25°C in a cool dry place.